[ad_1] A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of…
Intestinal microorganisms influence white blood cell levels in…
[ad_1] Intestinal bacteria composition is crucial to driving the recovery of neutrophils counts in the blood of mice following treatments such as stem cell transplants or chemotherapy. White blood cells, or granulocytes, are cells that…
Precision oncology approach shows potential for high-grade gliomas…
[ad_1] Researchers at the University of Michigan Rogel Cancer Center have identified a novel treatment approach to an aggressive type of pediatric brain cancer, using therapies already approved to treat cancer. "Our findings have immediate…
Miniature ‘bone marrows in a dish’ to improve…
[ad_1] Scientists from Oxford University and the University of Birmingham have made the first bone marrow 'organoids' that capture the key features of human bone marrow. This technology, which is the subject of a patent…
An enzyme that drives the growth of an…
[ad_1] An enzyme that drives the growth of an often-lethal childhood brain cancer may hold the key to a future treatment, says a McMaster University-led study. Researchers discovered that by blocking the production of an…
Making glioblastoma more vulnerable to treatment — ScienceDaily
[ad_1] In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment. Their target is SAMHD1, a protein which can protect us…
Phase 1 study results reported — ScienceDaily
[ad_1] Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat…
Experimental monoclonal antibodies show promise against Epstein-Barr virus…
[ad_1] A panel of investigational monoclonal antibodies (mAbs) targeting different sites of the Epstein-Barr virus (EBV) blocked infection when tested in human cells in a laboratory setting. Moreover, one of the experimental mAbs provided nearly…
Pro-drug curcumin shows clinical potential in mice —…
[ad_1] Curcumin, a natural molecule related to turmeric, has been used to treat cancer patients in cancer clinical studies. While it has documented antitumor effects, challenges involving its chemistry have caused drug development to lag.…
Scientists pinpoint druggable target in aggressive breast cancer…
[ad_1] Researchers at VCU Massey Cancer Center have set their sights on a new therapeutic target for an aggressive form of breast cancer with limited treatment options. Breast cancer is the second most common cancer…